Bioisosteric investigation of ebselen: Synthesis and in vitro characterization of 1,2-benzisothiazol-3(2H)-one derivatives as potent New Delhi metallo-β-lactamase inhibitors

Author:

Jin Wen Bin,Xu Chen,Cheung Qipeng,Gao Wei,Zeng Ping,Liu Jun,Chan Edward W.C.,Leung Yun-Chung,Chan Tak Hang,Wong Kwok-Yin,Chen Sheng,Chan Kin-Fai

Funder

Research Grants Council of Hong Kong

Research Grant Council of the Government of Hong Kong SAR

Innovation and Technology Commission, and the Hong Kong Polytechnic University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference56 articles.

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2. Antibacterial drug discovery in the resistance era;Brown;Nature,2016

3. Antibiotic Resistance by Enzyme Inactivation: From Mechanisms to Solutions;De Pascale;ChemBioChem,2010

4. Molecular mechanisms of antibiotic resistance;Blair;Nat. Rev. Microbiol.,2015

5. Mechanisms of β-lactam antimicrobial resistance and epidemiology of major community-and healthcare-associated multidrug-resistant bacteria;Tang;Adv. Drug Deliv. Rev.,2014

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