The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Biochemistry,Biophysics
Reference23 articles.
1. Cytochrome P450: Structure, Mechanism, and Biochemistry;Ortiz de Montellano,1995
2. P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes 1 1Abbreviations: FTI, farnesyl-protein transferase inhibitor; FTase, farnesyl-protein transferase; and LC-MS, liquid chromatography-mass spectrometry.
3. Perspective of Humanized Mouse Models for Assessing PK/PD and Toxic Profile of Drug Candidates in Preclinical Study
4. Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9
5. Cytochrome P450 2C9 Type II Binding Studies on Quinoline-4-Carboxamide Analogues
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum;Archives of Biochemistry and Biophysics;2024-04
2. The binding of nitrogen-donor ligands to the ferric and ferrous forms of cytochrome P450 enzymes;Journal of Inorganic Biochemistry;2023-05
3. To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme;Inorganic Chemistry;2021-12-15
4. Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights;Chemical Research in Toxicology;2021-03-26
5. Enzyme Kinetics of Oxidative Metabolism—Cytochromes P450;Methods in Molecular Biology;2021
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3