Cytochrome P450 2C9 Type II Binding Studies on Quinoline-4-Carboxamide Analogues
Author:
Affiliation:
1. Department of Chemistry, Washington State University, P.O. Box 644630, Pullman, Washington 99164-4630, and Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm8011257
Reference47 articles.
1. A NEW CLASS OF CYP2C9 INHIBITORS: PROBING 2C9 SPECIFICITY WITH HIGH-AFFINITY BENZBROMARONE DERIVATIVES
2. Charge and Substituent Effects on Affinity and Metabolism of Benzbromarone-Based CYP2C19 Inhibitors
3. Quantitative Binding Models for CYP2C9 Based on Benzbromarone Analogues
4. CLINICAL AND TOXICOLOGICAL RELEVANCE OF CYP2C9: Drug-Drug Interactions and Pharmacogenetics
5. Line-Walking Method for Predicting the Inhibition of P450 Drug Metabolism
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