Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases-Reference-Cited by-同舟云学术

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Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases

Published:2021-07 Issue: Volume:247 Page:109804
ISSN:0022-1139
Container-title:Journal of Fluorine Chemistry
language:en
Short-container-title:Journal of Fluorine Chemistry

Author:

Brewitz Lennart,Nakashima Yu,Tumber Anthony,Salah Eidarus,Schofield Christopher J.

Funder

Daiichi Sankyo Foundation of Life Science

Wellcome Trust

Biotechnology and Biological Sciences Research Council

Cancer Research UK

Deutsche Forschungsgemeinschaft

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Environmental Chemistry,Biochemistry

Reference59 articles.

1. 2-Oxoglutarate-Dependent Oxygenases,2015

2. Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway;Kaelin;Mol. Cell,2008

3. Roxadustat: First global approval;Dhillon;Drugs,2019

4. Inhibition of 2-oxoglutarate dependent oxygenases;Rose;Chem. Soc. Rev.,2011

5. Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase;Stenflo;Proc. Natl. Acad. Sci. USA,1989

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1. Methods for production and assaying catalysis of isolated recombinant human aspartate/asparagine-β-hydroxylase;Methods in Enzymology;2024

2. 5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5;Journal of Medicinal Chemistry;2023-08-01

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