5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5-Reference-Cited by-同舟云学术

5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5

Published:2023-08-01 Issue:15 Volume:66 Page:10849-10865
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brewitz Lennart¹^ORCID,Nakashima Yu¹,Piasecka Sonia K.²,Salah Eidarus¹,Fletcher Sally C.²,Tumber Anthony¹,Corner Thomas P.¹,Kennedy Tristan J.²,Fiorini Giorgia¹,Thalhammer Armin¹,Christensen Kirsten E.³,Coleman Mathew L.²,Schofield Christopher J.¹^ORCID

Affiliation:

1. Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, OX1 3TA Oxford, U.K.

2. Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, B15 2TT Birmingham, U.K.

3. Chemical Crystallography, Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, OX1 3TA Oxford, U.K.

Funder

Merck Sharp and Dohme

Vertex Pharmaceuticals

Daiichi Sankyo Foundation of Life Science

Deutsche Forschungsgemeinschaft

Wellcome Trust

GlaxoSmithKline

University of Birmingham

Japan Society for the Promotion of Science

Royal Commission for the Exhibition of 1851