Kinetic inhibitory profile of BIA 3-202, a novel fast tight-binding, reversible and competitive catechol-O-methyltransferase inhibitor

Author:

Bonifácio Maria João,Vieira-Coelho Maria Augusta,Soares-da-Silva Patrı́cio

Publisher

Elsevier BV

Subject

Pharmacology

Reference28 articles.

1. Enzymatic O-methylation of epinephrine and other catechols;Axelrod;J. Biol. Chem.,1958

2. New, selective catechol-O-methyltransferase inhibitors as therapeutic agents in Parkinson's disease;Bonifati;Pharmacol. Ther.,1999

3. A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding;Bradford;Anal. Biochem.,1976

4. Tight binding inhibitors: I. Kinetic behavior;Cha;Biochem. Pharmacol.,1975

5. Catechol-O-methyltransferase: pharmacological aspects and physiological role;Guldberg;Pharmacol. Rev.,1975

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