Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping-Reference-Cited by-同舟云学术

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Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping

Published:2021-12-22 Issue:1 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Loureiro Ana I.¹,Fernandes‐Lopes Carlos¹,Bonifácio Maria João¹,Sousa Filipa¹,Kiss László E.¹,Soares‐da‐Silva Patricio¹²³

Affiliation:

1. Department of Research and Development BIAL—Portela & Cª. S.A. S Mamede do Coronado Portugal

2. Unit of Pharmacology and Therapeutics Department of Biomedicine Faculty of Medicine University of Porto Porto Portugal

3. MedInUp—Center for Drug Discovery and Innovative Medicines University of Porto Porto Portugal

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.891

Reference26 articles.

1. Pharmacological profile of opicapone, a third‐generation nitrocatechol catechol‐O‐methyl transferase inhibitor, in the rat;Bonifacio MJ;Br J Pharmacol,2015

2. Discovery of a long‐acting, peripherally selective inhibitor of catechol‐O‐methyltransferase;Kiss LE;J Med Chem,2010

3. Brain and peripheral pharmacokinetics of levodopa in the cynomolgus monkey following administration of opicapone, a third generation nitrocatechol COMT inhibitor;Bonifacio MJ;Neuropharmacology,2014

4. Contemporary options for the management of motor complications in Parkinson's disease: updated clinical Review;Cabreira V;Drugs,2019

5. Opicapone for the treatment of Parkinson's disease: a review of a new licensed medicine;Fabbri M;Mov Disord,2018

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Human Absorption, Distribution, Metabolism, and Excretion Studies: Origins, Innovations, and Importance;Drug Metabolism and Disposition;2023-03-27

2. In vitro effects of opicapone on activity of human UDP-glucuronosyltransferases isoforms;Toxicology Letters;2022-08

3. Absorption, metabolism and excretion of opicapone in human healthy volunteers;British Journal of Clinical Pharmacology;2022-05-20

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