Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS-Reference-Cited by-同舟云学术

Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS

Published:2019-06 Issue:6 Volume:29 Page:1400-1409.e5
ISSN:1550-4131
Container-title:Cell Metabolism
language:en
Short-container-title:Cell Metabolism

Author:

Molinaro Angela,Becattini Barbara,Mazzoli Arianna,Bleve Augusto,Radici Lucia,Maxvall Ingela,Sopasakis Victoria Rotter,Molinaro Antonio,Bäckhed Fredrik,Solinas Giovanni

Funder

Swiss National Science Foundation

EFSD Diabetes and Cancer Programme

Cancerfonden

Swedish Research Council

Novo Nordisk Fonden

Diabetes Fonden

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference32 articles.

1. Insulin receptor signaling in normal and insulin-resistant states;Boucher;Cold Spring Harb. Perspect. Biol.,2014

2. Single-molecule study reveals how receptor and Ras synergistically activate PI3Kα and PIP3 signaling;Buckles;Biophys. J.,2017

3. Synergy in activating class I PI3Ks;Burke;Trends Biochem. Sci.,2015

4. Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis;Chattopadhyay;Diabetes,2011

5. Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport;Chaussade;Mol. Endocrinol.,2003

Cited by 74 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. “NO” controversy?: A controversial role in insulin signaling of diabetic encephalopathy;Molecular and Cellular Endocrinology;2024-11

2. Network analysis and experimental verification of Salvia miltiorrhiza Bunge-Reynoutria japonica Houtt. drug pair in the treatment of non-alcoholic fatty liver disease;BMC Complementary Medicine and Therapies;2024-08-14

3. DDX21 functions as a potential novel oncopromoter in pancreatic ductal adenocarcinoma: a comprehensive analysis of the DExD box family;Discover Oncology;2024-08-03

4. Clinical and pathological characteristics of gestational diabetes mellitus with different insulin resistance;Journal of Diabetes and its Complications;2024-08

5. Designing Small Molecule PI3Kγ Inhibitors: A Review of Structure-Based Methods and Computational Approaches;Journal of Medicinal Chemistry;2024-06-19