Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling-Reference-Cited by-同舟云学术

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Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling

Published:2017-12 Issue:11 Volume:113 Page:2396-2405
ISSN:0006-3495
Container-title:Biophysical Journal
language:en
Short-container-title:Biophysical Journal

Author:

Buckles Thomas C.,Ziemba Brian P.,Masson Glenn R.,Williams Roger L.,Falke Joseph J.

Funder

National Institutes of Health

Medical Research Council

AstraZeneca/LMB Blue Skies Initiative

St. Catharine’s College

Publisher

Elsevier BV

Subject

Biophysics

Reference42 articles.

1. Eukaryotic chemotaxis: a network of signaling pathways controls motility, directional sensing, and polarity;Swaney;Annu. Rev. Biophys.,2010

2. Cell signaling by receptor tyrosine kinases;Lemmon;Cell,2010

3. Requirement of phosphatidylinositol(3,4,5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation;Denley;Mol. Cancer Res.,2009

4. Targeting RAS signalling pathways in cancer therapy;Downward;Nat. Rev. Cancer,2003

5. Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA);Burke;Proc. Natl. Acad. Sci. USA,2012

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