Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding-Reference-Cited by-同舟云学术

Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding

Published:2002-08 Issue:16 Volume:12 Page:2149-2152
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chauret Nathalie,Guay Daniel,Li Chun,Day Stephen,Silva José,Blouin Marc,Ducharme Yves,Yergey James A.,Nicoll-Griffith Deborah A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. Genomic organization of the human phosphodiesterasePDE11Agene

2. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

3. Cyclic AMP-dependent Regulation of Lipid Mediators in White Cells: A Unifying Concept for Explaining the Efficacy of Theophylline in Asthma

4. Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors

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