A Journey of the Development of Privileged Difluorocarbene Reagents TMSCF<sub>2</sub>X (X = Br, F, Cl) for Organic Synthesis-Reference-Cited by-同舟云学术

A Journey of the Development of Privileged Difluorocarbene Reagents TMSCF₂X (X = Br, F, Cl) for Organic Synthesis

Published:2024-02-14 Issue:5 Volume:57 Page:693-713
ISSN:0001-4842
Container-title:Accounts of Chemical Research
language:en
Short-container-title:Acc. Chem. Res.

Author:

Xie Qiqiang¹,Hu Jinbo¹^ORCID

Affiliation:

1. Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai 200032, China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.3c00719

Reference104 articles.

1. Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

2. Synthesis of gem-Difluorinated Cyclopropanes and Cyclopropenes: Trifluoromethyltrimethylsilane as a Difluorocarbene Source

3. Efficient Difluoromethylation of Alcohols Using TMSCF2Br as a Unique and Practical Difluorocarbene Reagent under Mild Conditions

4. Controllable Single and Double Difluoromethylene Insertions into C–Cu Bonds: Copper-Mediated Tetrafluoroethylation and Hexafluoropropylation of Aryl Iodides with TMSCF₂H and TMSCF₂Br

5. Organofluorine Chemistry

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Fluorinated building blocks in drug design: new pathways and targets;Future Medicinal Chemistry;2024-07-17

2. Palladium(II) Difluorocarbene-Involved Catalytic Coupling with Benzyl/Allyl Electrophiles;CCS Chemistry;2024-07-11

3. Batch and Continuous-Flow Electrochemical Geminal Difluorination of Indeno[1,2-c]furans;Organic Letters;2024-07-05

4. Difluoromethyl phenoxathiinium salt: a new general and versatile difluoromethylating reagent;SCIENTIA SINICA Chimica;2024-05-28

5. Expedient Synthesis of gem-CF2-2H-Thiophenes from Enaminothiones;Synlett;2024-04-08