Successful Prediction of Human Pharmacokinetics After Oral Administration by Optimized Physiologically Based Pharmacokinetics Approach and Permeation Assay Using Human Induced Pluripotent Stem Cell–Derived Intestinal Epithelial Cells
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference73 articles.
1. The successes and failures of physiologically based pharmacokinetic modeling: there is room for improvement;Poggesi;Expert Opin Drug Metab Toxicol,2014
2. Successful prediction of human pharmacokinetics by improving calculation processes of physiologically based pharmacokinetic approach;Mayumi;J Pharm Sci,2019
3. In vitro-in vivo extrapolation of clearance: modeling hepatic metabolic clearance of highly bound drugs and comparative assessment with existing calculation methods;Poulin;J Pharm Sci,2012
4. Toward a new paradigm for the efficient in vitro-in vivo extrapolation of metabolic clearance in humans from hepatocyte data;Poulin;J Pharm Sci,2013
5. Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats;Sawada;J Pharmacokinet Biopharm,1985
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