Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9

Author:

McLeod H.L.,Graham M.A.,Aamdal S.,Setanoians A.,Groot Y.,Lund B.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference12 articles.

1. Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent;Verweij;Oncology Res,1994

2. EO9: a novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models;Hendriks;Eur J Cancer,1993

3. Pharmacokinetics, distribution, and metabolism of the novel bioreductive alkylating indoloquinone EO9 in rodents;Workman;Int J Radiat Oncol Biol Phys,1992

4. Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug EO9;Schellens;J Natl Cancer Inst,1994

5. Phase I study of the bioreductive indoloquinone EO9;Lund;Ann Oncol,1994

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