Pharmacokinetics, distribution, and metabolism of the novel bioreductive alkylating indoloquinone EO9 in rodents

Author:

Workman P,Binger M,Kooistra K.L

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,Radiation

Reference9 articles.

1. Bailey, S. M.; Suggett, N.; Walton M. E.; Workman P. Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones. Int. J. Radiat. Oncol. Biol. Phys. (In press.)

2. Gradient high-performance liquid chromatographic assay for the determination of the novel indoloquinone antitumour agent EO9 in biological specimens;Binger;J. Chromatog.,1990

3. Potential roles for preclinical pharmacology in phase I clinical trials;Collins;Cancer Treat. Rep.,1986

4. Pharmacokinetically-guided dose escalation in Phase I clinical trials;Eur. J. Cancer,1987

5. Mitomycin analogues. I. Indoloquinones as (potential) bisalkylating agents;Oostveen;Tetrahedron,1987

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