Scaffold selection and scaffold hopping in lead generation: a medicinal chemistry perspective
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference37 articles.
1. The role of the medicinal chemist in drug discovery — then and now;Lombardino;Nat. Rev. Drug Discov.,2004
2. Hit and lead generation: beyond high-throughput screening;Bleicher;Nat. Rev. Drug Discov.,2003
3. Components of successful lead generation;Davis;Curr. Top. Med. Chem.,2005
4. Lead generation - enhancing the success of drug discovery by investing in the hit to lead process;Alanine;Comb. Chem. High Throughput Screen.,2003
5. The hit-to-lead process at Schering AG: strategic aspects;Steinmeyer;ChemMedChem,2006
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