Liquid chromatography–mass spectrometry in in vitro drug metabolite screening
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference102 articles.
1. Prediction of drug metabolism and interactions on the basis of in vitro investigations;Pelkonen;Basic Clin. Pharmacol. Toxicol.,2005
2. Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54;Coecke;Altern. Lab. Anim.,2006
3. ADME/PK as part of a rational approach to drug discovery;Eddershaw;Drug Discov. Today,2000
4. Drug metabolism and pharmacokinetics in drug discovery;Roberts;Curr. Opin. Drug Discov. Dev.,2003
5. LC/MS applications in drug development;Lee;Mass Spectrom. Rev.,1999
Cited by 120 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Ion Trap LC/MS reveals the generation of reactive intermediates in acalabrutinib metabolism: phase I metabolic profiling and bioactivation pathways elucidation;RSC Advances;2024
2. Metabolic profiles of Fufang Xiling Jiedu capsule in rats by ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry;Journal of Separation Science;2024-01
3. In Vitro and Reactive Metabolites Investigation of Metabolic Profiling of Tyrosine Kinase Inhibitors Dubermatinib in HLMs by LC–MS/MS;Separations;2023-06-13
4. Investigation of Fenebrutinib Metabolism and Bioactivation Using MS3 Methodology in Ion Trap LC/MS;Molecules;2023-05-22
5. Piperazine ring toxicity in three novel anti-breast cancer drugs: an in silico and in vitro metabolic bioactivation approach using olaparib as a case study;Naunyn-Schmiedeberg's Archives of Pharmacology;2023-02-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3