Frontiers in PROTACs
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference49 articles.
1. Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system;Dou;Curr Cancer Drug Targets,2014
2. An affinity-directed protein missile system for targeted proteolysis;Fulcher;Open Biology,2016
3. bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA);Lim;Proc Natl Acad Sci U S A,2020
4. Rational discovery of molecular glue degraders via scalable chemical profiling;Mayor-Ruiz;Nat Chem Biol,2020
5. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K;Słabicki;Nature,2020
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2. Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches;Drug Design, Development and Therapy;2024-06
3. Structural Considerations and Chemistry of PROTACs;PROTAC-Mediated Protein Degradation: A Paradigm Shift in Cancer Therapeutics;2024
4. Delivery Systems: Miniaturised PROTAC, Nano PROTAC, and Aptamer-Based RNA PROTAC;PROTAC-Mediated Protein Degradation: A Paradigm Shift in Cancer Therapeutics;2024
5. N-Heterocycle based Degraders (PROTACs) Manifesting Anticancer Efficacy: Recent Advances;Current Drug Targets;2023-11
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