Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition-Reference-Cited by-同舟云学术

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Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition

Published:2014-09 Issue:6 Volume:8 Page:1919-1929
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Bolden Jessica E.,Tasdemir Nilgun,Dow Lukas E.,van Es Johan H.,Wilkinson John E.,Zhao Zhen,Clevers Hans,Lowe Scott W.

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference28 articles.

1. BET domain co-regulators in obesity, inflammation and cancer;Belkina;Nat. Rev. Cancer,2012

2. Regeneration of intestinal stem/progenitor cells following doxorubicin treatment of mice;Dekaney;Am. J. Physiol. Gastrointest. Liver Physiol.,2009

3. BET bromodomain inhibition as a therapeutic strategy to target c-Myc;Delmore;Cell,2011

4. Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription;Dey;Mol. Biol. Cell,2009

5. A pipeline for the generation of shRNA transgenic mice;Dow;Nat. Protoc.,2012

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