A pipeline for the generation of shRNA transgenic mice-Reference-Cited by-同舟云学术

A pipeline for the generation of shRNA transgenic mice

Published:2012-02 Issue:2 Volume:7 Page:374-393
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Dow Lukas E,Premsrirut Prem K,Zuber Johannes,Fellmann Christof,McJunkin Katherine,Miething Cornelius,Park Youngkyu,Dickins Ross A,Hannon Gregory J,Lowe Scott W

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2011.446.pdf

Reference31 articles.

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3. Stegmeier, F., Hu, G., Rickles, R.J., Hannon, G.J. & Elledge, S.J. A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 102, 13212–13217 (2005).

4. Premsrirut, P.K. et al. A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell 145, 145–158 (2011).

5. Grimm, D. et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441, 537–541 (2006).

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