The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus-Reference-Cited by-同舟云学术

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The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus

Published:2019-02 Issue:9 Volume:26 Page:2377-2393.e13
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Gentili Matteo,Lahaye Xavier,Nadalin Francesca,Nader Guilherme P.F.,Puig Lombardi Emilia,Herve Solène,De Silva Nilushi S.,Rookhuizen Derek C.,Zueva Elina,Goudot Christel,Maurin Mathieu,Bochnakian Aurore,Amigorena Sebastian,Piel Matthieu,Fachinetti Daniele,Londoño-Vallejo Arturo,Manel Nicolas^ORCID

Funder

LABEX VRI

LABEX DCBIOL

ANR INNATENUCLEOTIDES

Fondation BMS

ACTERIA Foundation

Fondation Schlumberger pour l’Education et la Recherche

ANRS

Sidaction

DIM Biothérapies

European Research Council

French Ministry of Education, Research, and Technology

Marie Skłodowska-Curie Individual Fellowship

EMBO Long-term fellowship

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference52 articles.

1. cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders;Andreeva;Nature,2017

2. Monocyte-derived dendritic cells do not proliferate and are not susceptible to retroviral transduction;Ardeshna;Br. J. Haematol.,2000

3. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes;Cerboni;J. Exp. Med.,2017

4. Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing;Chen;Nat. Immunol.,2016

5. Structural mechanism of cytosolic DNA sensing by cGAS;Civril;Nature,2013

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1. Protein-protein interactions in cGAS-STING pathway: a medicinal chemistry perspective;Future Medicinal Chemistry;2024-09-12

2. Epigenetic regulation of cGAS and STING expression in cancer;International Immunopharmacology;2024-09

3. A novel role for CSA in the regulation of nuclear envelope integrity: uncovering a non-canonical function;Life Science Alliance;2024-08-29

4. The Arp2/3 inhibitory protein Arpin inhibits homology‐directed DNA repair;Biology of the Cell;2024-08-09

5. Cyclic GMP-AMP synthase recognizes the physical features of DNA;Acta Pharmacologica Sinica;2024-08-07

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