Protein-protein interactions in cGAS-STING pathway: a medicinal chemistry perspective-Reference-Cited by-同舟云学术

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Protein-protein interactions in cGAS-STING pathway: a medicinal chemistry perspective

Published:2024-09-12 Issue: Volume: Page:1-20
ISSN:1756-8919
Container-title:Future Medicinal Chemistry
language:en
Short-container-title:Future Medicinal Chemistry

Author:

Zhang Shi-Duo¹²,Li Hui¹²,Zhou Ye-Ling¹²,Liu Xue-Chun¹²,Li De-Chang¹²,Hao Chuan-Feng¹²,You Qi-Dong¹²,Xu Xiao-Li¹²^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines, Jiang Su Key Laboratory of Drug Design & Optimization, China Pharmaceutical University, Nanjing, 210009, China

2. Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China

Funder

National Natural Science Foundation of China

the Project Program of State Key Laboratory of Natural Medicines

the Qinglan Project of Jiangsu Province

Original exploration project of China Pharmaceutical University

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/17568919.2024.2383164

Reference120 articles.

1. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

2. The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

3. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

4. Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

5. Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP

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