cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders-Reference-Cited by-同舟云学术

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders

Published:2017-09 Issue:7672 Volume:549 Page:394-398
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Andreeva Liudmila,Hiller Björn,Kostrewa Dirk,Lässig Charlotte,de Oliveira Mann Carina C.,Jan Drexler David,Maiser Andreas,Gaidt Moritz,Leonhardt Heinrich,Hornung Veit,Hopfner Karl-Peter

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature23890.pdf

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3. Sun, L., Wu, J., Du, F., Chen, X. & Chen, Z. J. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339, 786–791 (2013)

4. Zhang, X. et al. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol. Cell 51, 226–235 (2013)

5. Chen, Q., Sun, L. & Chen, Z. J. Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing. Nat. Immunol. 17, 1142–1149 (2016)

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