Switching the reactivity of cyanomethylpyridinium salts in the 1,3-cycloaddition conditions with alkyl propiolates to cyanoindolizines or cyanoazaindolizinyl-indolizines
Author:
Funder
Ministerul Cercetării şi Inovării
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference27 articles.
1. Synthesis and antiproliferative activity of indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line
2. Discovery of protein–protein binding disruptors using multi-component condensations small molecules
3. Efficient synthesis and characterization of novel indolizines: exploration of in vitro COX-2 inhibitory activity and molecular modelling studies
4. Amberlite–IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products
5. Facile three-component domino reactions in the regioselective synthesis and antimycobacterial evaluation of novel indolizines and pyrrolo[2,1-a]isoquinolines
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1. Addition Reactions: Cycloaddition;Organic Reaction Mechanisms Series;2024-03-15
2. Cyanomethyl pyridinium and isoquinolinium salts: a versatile chemical reagent for the synthesis of annulated heterocycles;Chemical Papers;2023-10-01
3. 1,3-Dipolar cycloaddition of cycloimmonium salts and 4-(trimethylsilyl)-3-butyn-2-one to access new functionalized indolizines with potential cytostatic activity;New Journal of Chemistry;2023
4. Indolizines and Their Hetero/Benzo Derivatives in Reactions of [8+2] Cycloaddition;Molecules;2021-04-03
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