Efficient synthesis and characterization of novel indolizines: exploration of in vitro COX-2 inhibitory activity and molecular modelling studies

Author:

Chandrashekharappa Sandeep12345ORCID,Venugopala Katharigatta N.678910ORCID,Tratrat Christophe1112131415ORCID,Mahomoodally Fawzi M.1617181920ORCID,Aldhubiab Bandar E.1112131415ORCID,Haroun Michelyne1112131415ORCID,Venugopala Rashmi212223910,Mohan Mahendra K.12345,Kulkarni Rashmi S.24252627,Attimarad Mahesh V.1112131415ORCID,Harsha Sree1112131415ORCID,Odhav Bharti678910

Affiliation:

1. Institute for Stem Cell Biology and Regenerative Medicine

2. NCBS

3. TIFR

4. GKVK

5. Bangalore 560 065

6. Department of Biotechnology and Food Technology

7. Faculty of Applied Science

8. Durban University of Technology

9. Durban 4001

10. South Africa

11. Department of Pharmaceutical Sciences

12. College of Clinical Pharmacy

13. King Faisal University

14. Al-Ahsa 31982

15. Kingdom of Saudi Arabia

16. Department of Health Sciences

17. Faculty of Science

18. University of Mauritius

19. Réduit

20. Mauritius

21. Department of Public Health Medicine

22. University of KwaZulu-Natal

23. Howard College Campus

24. Department of Chemistry

25. Jain University

26. Bangalore 560 019

27. India

Abstract

Novel indolizine scaffolds as COX-2 inhibiting agents.

Funder

Durban University of Technology

National Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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