Regional brain mGlu5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers

Author:

Streffer Johannes,Treyer Valerie,Buck Alfred,Ametamey Simon M.,Blagoev Milen,Maguire Ralph PORCID,Gautier Aurélie,Auberson Yves P.ORCID,Schmidt Mark E.ORCID,Vranesic Ivan-Toma,Gomez-Mancilla Baltazar,Gasparini Fabrizio

Funder

Novartis

Publisher

Elsevier BV

Subject

Cognitive Neuroscience,Neurology

Reference28 articles.

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3. Human PET studies of metabotropic glutamate receptor subtype 5 with 11C-ABP688;Ametamey;J. Nucl. Med.,2007

4. AFQ056 treatment of levodopa-induced dyskinesias: results of 2 randomized controlled trials;Berg;Mov. Disord.,2011

5. Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome;Dolen;J. Physiol.,2008

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