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Asymmetry and dynamics in bis-intercalated DNA

Published:1995-06 Issue:6 Volume:3 Page:693-699
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Peek Mary Elizabeth,Lipscomb Leigh Ann,Haseltine John,Gao Qi,Roques Bernard P.,Garbay-Jaureguiberry Christiane,Williams Loren Dean

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. A diacridine derivative that binds by bisintercalation at two contiguous sites on DNA

2. DNA bifunctional intercalators. 1. Synthesis and conformational properties of an ethidium homodimer and of an acridine ethidium heterodimer

3. DNA intercalating compounds as potential antitumor agents. 2. Preparation and properties of 7H-pyridocarbazole dimers

4. DNA bifunctional intercalators: Antileukemic activity of new pyridocarbazole dimers

5. Induction of an abortive and futile DNA repair process inE.coliby the antitumor DNA bifunctional intercalator, ditercalinium: role inpolAin death induction

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1. DNA major versus minor groove occupancy of monomeric and dimeric crystal violet derivatives. Toward structural correlations;Bioorganic & Medicinal Chemistry;2023-10

2. Scaffolds in cytotoxic drugs and novel antitumor molecules interacting with nucleic acids;Privileged Scaffolds in Drug Discovery;2023

3. Dimeric and trimeric derivatives of the azinomycin B chromophore show enhanced DNA binding;Organic & Biomolecular Chemistry;2017

4. Synthesis and in vitro biological evaluation of new pyrazole chalcones and heterocyclic diamides as potential anticancer agents;Arabian Journal of Chemistry;2015-05

5. Contribution of phenylalanine side chain intercalation to the TATA-box binding protein–DNA interaction: molecular dynamics and dispersion-corrected density functional theory studies;Journal of Molecular Modeling;2014-10-30

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