Clinical development of the oral gonadotropin-releasing hormone antagonist elagolix
Author:
Publisher
Elsevier BV
Subject
Obstetrics and Gynecology,Reproductive Medicine,Embryology
Reference12 articles.
1. Dose-dependent suppression of gonadotropins and ovarian hormones by elagolix in healthy premenopausal women;Ng;J Clin Endocrinol Metab,2017
2. Progress towards the development of non-peptide orally-active gonadotropin-releasing hormone (GnRH) antagonists: therapeutic implications;Millar;Br Med Bull,2000
3. 3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally Active Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design, Synthesis, and in Vitro and in Vivo Characterization
4. Discovery of Sodium R-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor
5. Clinical evaluation of the oral gonadotropin-releasing hormone-antagonist elagolix for the management of endometriosis-associated pain;Taylor;Pain Manag,2019
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