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Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin

  • Published:2017-09 Issue: Volume:984 Page:211-222
  • ISSN:0003-2670
  • Container-title:Analytica Chimica Acta
  • language:en
  • Short-container-title:Analytica Chimica Acta

Author:

Farcaş E.,Bouckaert C.,Servais A.-C.,Hanson J.ORCID,Pochet L.,Fillet M.

Funder

“Fonds spéciaux” of the University of Liège

FNRS

“Fonds Léon Frédéric”

Belgium National Fund for Scientific Research (FNRS)

Publisher

Elsevier BV

Subject

Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference41 articles.

1. Twenty years on: the impact of fragments on drug discovery;Erlanson;Nat. Rev. Drug Discov.,2016

2. Fragment-based Drug Discovery: Lessons and Outlook;Erlanson,2016

3. A decade of fragment-based drug design: strategic advances and lessons learned;Hajduk;Nat. Rev. Drug Discov.,2007

4. Screening-based approaches to identify small molecules that inhibit protein-protein interactions;Choi;Expert Opin. Drug Discov.,2017

5. Fragment-based drug discovery using NMR spectroscopy;Harner;J. Biomol. NMR,2013
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