Fragment-based drug discovery using NMR spectroscopy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Spectroscopy,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s10858-013-9740-z.pdf
Reference76 articles.
1. Baell JB (2010) Observations on screening-based research and some concerning trends in the literature. Future Med Chem 2:1529–1546
2. Baell JB, Holloway GA (2010) New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. J Med Chem 53:2719–2740
3. Becattini B, Pellecchia M (2006) SAR by ILOEs: an NMR-based approach to reverse chemical genetics. Chemistry 12:2658–2662
4. Becattini B, Culmsee C, Leone M, Zhai D, Zhang X, Crowell KJ, Rega MF, Landshamer S, Reed JC, Plesnila N et al (2006) Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid. Proc Natl Acad Sci USA 103:12602–12606
5. Bohm HJ, Florh A, Stahl M (2004) Scaffold hopping. Drug Discov Today 1:217–224
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