Method development and validation of the simultaneous determination of a novel topoisomerase 1 inhibitor, the prodrug, and the active metabolite in human plasma using column-switching LC–MS/MS, and its application in a clinical trial-Reference-Cited by-同舟云学术

Method development and validation of the simultaneous determination of a novel topoisomerase 1 inhibitor, the prodrug, and the active metabolite in human plasma using column-switching LC–MS/MS, and its application in a clinical trial

Published:2011-11 Issue:30 Volume:879 Page:3415-3422
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Kamei Tomonori,Uchimura Takahide,Nishimiya Kazuhiro,Kawanishi Takehiko

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

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1. Synthesis of new camptothecin analogs with improved antitumor activities

2. Flat-Fixed Dosing of Irinotecan

3. Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog

4. Determinants of CPT-11 and SN-38 activities in human lung cancer cells

5. Human ABC Transporter ABCG2 in Xenobiotic Protection and Redox Biology

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