Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog-Reference-Cited by-同舟云学术

Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog

Published:2009-05 Issue:10 Volume:19 Page:2772-2776
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ohwada Jun,Ozawa Sawako,Kohchi Masami,Fukuda Hiroshi,Murasaki Chikako,Suda Hitomi,Murata Takeshi,Niizuma Satoshi,Tsukazaki Masao,Ori Kazutomo,Yoshinari Kiyoshi,Itezono Yoshiko,Endo Mika,Ura Masako,Tanimura Hiromi,Miyazaki Yoko,Kawashima Akira,Nagao Shunsuke,Namba Eitarou,Ogawa Koutarou,Kobayashi Kazuko,Okabe Hisafumi,Umeda Isao,Shimma Nobuo

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

2. A New Water-soluble Camptothecin Derivative, DX-8951f, Exhibits Potent Antitumor Activity against Human Tumorsin vitroandin vivo

3. Clinical Pharmacokinetics of Irinotecan

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