Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC–MS/MS) assay for simultaneous quantifications of CZ48, lactone-stabilized camptothecin, and camptothecin and their pharmacokinetic and biliary evaluations in rats
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference23 articles.
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3. Sulfuric acid catalyzed preparation of alkyl and alkenyl camptothecin ester derivatives and antitumor activity against human xenografts grown in nude mice;Cao;Open J. Med. Chem.,2012
4. Enhanced lactone stability of CZ48 in blood correlates to its lack of toxicity in mice;Liu;J. Pharm. Pharm. Sci.,2013
5. Alkyl esters of camptothecin and 9-nitrocamptothecin: synthesis, in vitro pharmacokinetics, toxicity, and antitumor activity;Cao;J. Med. Chem.,1998
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