Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717 This paper is dedicated to Professor Heinz Floss, a pioneer in the field of antibiotics, on the occasion of his 65th birthday. The GenBank accession numbers for the sequences reported in this paper are AF164960 and AF164961.-Reference-Cited by-同舟云学术

Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717 This paper is dedicated to Professor Heinz Floss, a pioneer in the field of antibiotics, on the occasion of his 65th birthday. The GenBank accession numbers for the sequences reported in this paper are AF164960 and AF164961.

Published:2000-01-01 Issue:1 Volume:146 Page:147-154
ISSN:1350-0872
Container-title:Microbiology
language:en
Short-container-title:

Author:

Faust B.¹,Hoffmeister D.¹,Weitnauer G.¹,Westrich L.¹,Haag S.²,Schneider P.¹,Decker H.²,Künzel E.³,Rohr J.³,Bechthold A.¹

Affiliation:

1. Universität Tübingen, Pharmazeutisches Institut, Auf der Morgenstelle 8, D-72076 Tübingen, Germany1

2. Hoechst Marion Roussel Deutschland GmbH, Process Development, D-65926 Frankfurt, Germany2

3. Medical University of South Carolina, Department of Pharmaceutical Sciences, 171 Ashley Avenue, Charleston, SC 29425-2303, USA3

Publisher

Microbiology Society

Subject

Microbiology

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2. Overexpression of the thiostrepton resistance gene from Streptomyces azureus in Escherichia coli and characterization of recognition sites of the 23S rRNA A1067 2′-methyltransferase in the guanosine triphosphate center of 23S ribosomal RNA;Bechthold;Eur J Biochem,1994

3. Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tü2717, which carries the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation;Decker;J Bacteriol,1995

4. A general approach for cloning and characterizing dNDP-glucose dehydratase genes from actinomycetes;Decker;FEMS Microbiol Lett,1996

5. Metabolic products of microorganisms. 234. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. 1. Isolation, characterization and biological properties;Drautz;J Antibiot,1986

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