Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386-Reference-Cited by-同舟云学术

Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

Published:2022-05-30 Issue:5 Volume:4 Page:
ISSN:2516-8290
Container-title:Access Microbiology
language:en
Short-container-title:

Author:

McHugh Rebecca E.¹²,Munnoch John T.²,Roe Andrew J.¹,Hoskisson Paul A.²^ORCID

Affiliation:

1. *Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, G12 8TA, UK

2. Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK

Abstract

We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.

Funder

Biotechnology and Biological Sciences Research Council

Royal Academy of Engineering

Medical Research Council

Publisher

Microbiology Society

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