A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium-Reference-Cited by-同舟云学术

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A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium

Published:2010-12-08 Issue:2 Volume:64 Page:197-203
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Kimura Kyota,Iwatsuki Masato,Nagai Takeshi,Matsumoto Atsuko,Takahashi Yoko,Shiomi Kazuro,Ōmura Satoshi,Abe Akio

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja2010155.pdf

Reference43 articles.

1. Cornelis, G. R. & Van Gijsegem, F. Assembly and function of type III secretory systems. Annu. Rev. Microbiol. 54, 735–774 (2000).

2. Bhavsar, A. P., Guttman, J. A. & Finlay, B. B. Manipulation of host-cell pathways by bacterial pathogens. Nature. 449, 827–834 (2007).

3. Croxen, M. A. & Finlay, B. B. Molecular mechanisms of Escherichia coli pathogenicity. Nat. Rev. Microbiol. 8, 26–38.

4. Donnenberg, M. S. & Kaper, J. B. Enteropathogenic Escherichia coli. Infect. Immun. 60, 3953–3961 (1992).

5. McDaniel, T. K., Jarvis, K. G., Donnenberg, M. S. & Kaper, J. B. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc. Natl Acad. Sci. USA 92, 1664–1668 (1995).

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