Complete microbial genomes for public health in Australia and the Southwest Pacific

Author:

Baines Sarah L.1ORCID,da Silva Anders Gonçalves2ORCID,Carter Glen P.1ORCID,Jennison Amy3ORCID,Rathnayake Irani3ORCID,Graham Rikki M.3ORCID,Sintchenko Vitali45ORCID,Wang Qinning5ORCID,Rockett Rebecca J.45ORCID,Timms Verlaine J.45ORCID,Martinez Elena5,Ballard Susan2ORCID,Tomita Takehiro2ORCID,Isles Nicole2ORCID,Horan Kristy A.2,Pitchers William2ORCID,Stinear Timothy P.1ORCID,Williamson Deborah A.21ORCID,Howden Benjamin P.21ORCID,Seemann Torsten12ORCID,

Affiliation:

1. Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria 3001, Australia

2. Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3001, Australia

3. Public Health Microbiology, Queensland Reference Centre for Microbial and Public Health Genomics, Forensic and Scientific Services, Queensland Department of Health, Archerfield, Queensland 4108, Australia

4. Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, New South Wales 2006, Australia

5. Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital and NSW Health Pathology, Sydney, New South Wales 2145, Australia

Abstract

Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health laboratory activities. Here, we announce a BioProject (PRJNA556438) dedicated to sharing complete genomes chosen to represent a range of pathogenic bacteria with regional importance to Australia and the Southwest Pacific; enriching the catalogue of globally available complete genomes for public health while providing valuable strains to regional public health microbiology laboratories. In this first step, we present 26 complete high-quality bacterial genomes. Additionally, we describe here a framework for reconstructing complete microbial genomes and highlight some of the challenges and considerations for accurate and reproducible genome reconstruction.

Publisher

Microbiology Society

Subject

General Medicine

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