The Regulatory Role of Different Exercises in Irisin, Heat Shock Protein 70 and Some Biochemical Parameters

Abstract

Background: It is known that exercise causes many changes in the human organism. Understanding the metabolisms underlying these changes is an important issue. The aim of the study was to determine the effects of different and regularly applied exercise programs on irisin, heat shock protein 70 and some biochemical parameters. Methods: 120 male university students participated in the study. Participants were divided into 4 equal groups as control (C), resistance exercise group (RE), high intensity interval (HIIT) and aerobic exercise group (AE). While the control group did not perform any exercise, the pre-determined exercise programs were applied to the other groups for 8 weeks and 3 days in a week. Blood samples were taken from all participants before and after the exercise program. Cholesterol, HDL and LDL cholesterol, triglyceride, creatine kinase (CK), lactate dehydrogenase (LDH), Irisin and Heat shock protein 70 (HSP70) levels were analyzed in blood samples. Results: It is determined that there are significant differences in pre-posttest values ​​of the AE group’s LDH, cholesterol, HDL, Triglyceride and HSP 70 levels, HIIT group’s CK, LDH, Cholesterol, HDL, Triglyceride, Irisin and HSP70 levels and RE group’s CK, LDH, Cholesterol, LDL, Triglyceride and irisin levels (p<0.05). Conlusions: It can be said that; exercise can correct abnormalities in lipid profile, changes in HSP70 levels may vary depending on muscle damage, the increase of irisin due to exercise.