Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice-Reference-Cited by-同舟云学术

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

Published:2017-03 Issue:379 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

De Palma Giada¹^ORCID,Lynch Michael D. J.²^ORCID,Lu Jun¹,Dang Vi T.³,Deng Yikang¹,Jury Jennifer¹,Umeh Genevieve¹^ORCID,Miranda Pedro M.¹,Pigrau Pastor Marc¹^ORCID,Sidani Sacha¹^ORCID,Pinto-Sanchez Maria Ines¹^ORCID,Philip Vivek¹,McLean Peter G.⁴,Hagelsieb Moreno-Gabriel⁵^ORCID,Surette Michael G.¹,Bergonzelli Gabriela E.⁴^ORCID,Verdu Elena F.¹,Britz-McKibbin Philip³^ORCID,Neufeld Josh D.²^ORCID,Collins Stephen M.¹,Bercik Premysl¹^ORCID

Affiliation:

1. Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

2. Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.

3. Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada.

4. Nestlé Research Center, Lausanne, Switzerland.

5. Department of Biology, Wilfrid Laurier University, Waterloo, Ontario, Canada.

Abstract

Fecal microbiota transplants from patients with irritable bowel syndrome and anxiety alter gut function and behavior in germ-free mice.

Funder

Canadian Institutes of Health Research

Hamilton Health Sciences

CIHR