Da-Jian-Zhong decoction alleviates diarrhea-predominant irritable bowel syndrome via modulation of gut microbiota and Th17/Treg balance

Author:

Zhang Meng-meng,Dang Ming,Wu Xu,Ou Li,Li Min,Zhao Chong-bo,Wei Pei-feng,Dong Tai-wei,Li Yao,Wu Chun-jie

Funder

National Natural Science Foundation of China

Education Department of Shaanxi Province

Publisher

Elsevier BV

Reference52 articles.

1. Immune activation in irritable bowel syndrome: what is the evidence?;Aguilera-Lizarraga;Nat. Rev. Immunol.,2022

2. Daikenchuto ameliorates muscle hypercontractility in a murine T-cell-mediated persistent gut motor dysfunction model;Akiho;Digestion,2011

3. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome;Barbara;Gastroenterology,2004

4. Colonic immune cells in irritable bowel syndrome: a systematic review and meta‐analysis;Bashashati;Neuro Gastroenterol. Motil.,2018

5. Systemic cytokines are elevated in a subset of patients with irritable bowel syndrome but largely unrelated to symptom characteristics;Bennet;Neuro Gastroenterol. Motil.,2018

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