Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents-Reference-Cited by-同舟云学术

Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents

Published:2020-07-22 Issue:553 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Keppeler Daniel¹²^ORCID,Schwaerzle Michael³⁴^ORCID,Harczos Tamas¹⁵^ORCID,Jablonski Lukasz¹⁵^ORCID,Dieter Alexander¹²^ORCID,Wolf Bettina¹⁵^ORCID,Ayub Suleman³⁴,Vogl Christian¹⁶^ORCID,Wrobel Christian¹⁷^ORCID,Hoch Gerhard¹⁵,Abdellatif Khaled¹⁵,Jeschke Marcus¹⁵^ORCID,Rankovic Vladan¹⁵,Paul Oliver³⁴^ORCID,Ruther Patrick³⁴^ORCID,Moser Tobias¹²⁵⁶⁸^ORCID

Affiliation:

1. Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37099 Göttingen, Germany.

2. Göttingen Graduate Center for Neurosciences and Molecular Biosciences, University of Göttingen, 37075 Göttingen, Germany.

3. University of Freiburg, Department of Microsystems Engineering (IMTEK), 79110 Freiburg, Germany.

4. Cluster of Excellence BrainLinks-BrainTools, University of Freiburg, 79110 Freiburg, Germany.

5. Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany.

6. Collaborative Research Center 889, University of Göttingen, 37075 Göttingen, Germany.

7. Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Göttingen, 37099 Göttingen, Germany.

8. Multiscale Bioimaging Cluster of Excellence, University Medical Center Göttingen, 37075 Göttingen, Germany.

Abstract

Optogenetic hearing restoration in rodents by LED-based multichannel optical cochlear implants provides improved spectral selectivity.

Funder

European Research Council

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference47 articles.

1. WHO Deafness and hearing loss. World Health Organ. (2018); http://www.who.int/news-room/fact-sheets/detail/deafness-and-hearing-loss.

2. Gene therapy for deafness: How close are we?

3. Gene therapy for the inner ear

4. Quo vadis, hair cell regeneration?

5. Cochlear Implants: System Design, Integration, and Evaluation

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