Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model.-Reference-Cited by-同舟云学术

Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model.

Published:2019-03 Issue:3 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Ao Ying¹²,Zhang Jie¹,Liu Zuojun¹,Qian Minxian¹,Li Yao³,Wu Zhuping¹,Sun Pengfei¹,Wu Jie¹,Bei Weixin¹,Wen Junqu¹,Wu Xuli³,Li Feng²,Zhou Zhongjun⁴^ORCID,Zhu Wei-Guo¹^ORCID,Liu Baohua¹^ORCID,Wang Zimei¹^ORCID

Affiliation:

1. Guangdong Key Laboratory of Genome Stability and Human Disease Prevention, Carson International Cancer Center, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Health Science Center, Shenzhen 518060, China.

2. Department of Genetics, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China.

3. School of Public Health, Shenzhen University Health Science Center, Shenzhen 518060, China.

4. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong.

Abstract

The causative progeria lamin A mutation inhibits CK2 enzyme activity to accelerate aging in laboratory mice.

Funder

National Natural Science Foundation of China

Discipline Construction Funding of Shenzhen

Shenzhen Municipal Commission of Science and Technology Innovation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

2. The nucleoskeleton as a genome-associated dynamic 'network of networks;Simon D. N.;Nat. Rev. Mol. Cell Biol.,2011

3. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice;Pendás A. M.;Nat. Genet.,2002

4. Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

5. A Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria

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