Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase–deficient mice

Published:2002-04-01 Issue:1 Volume:31 Page:94-99
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Pendás Alberto M.,Zhou Zhongjun,Cadiñanos Juan,Freije José M.P.,Wang Jianming,Hultenby Kjell,Astudillo Aurora,Wernerson Annika,Rodríguez Francisco,Tryggvason Karl,López-Otín Carlos

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng871z.pdf

Reference18 articles.

1. Freije, J.M.P. et al. Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins. Genomics 58, 270–280 (1999).

2. Tam, A. et al. Dual roles for Zmpste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J. Cell Biol. 142, 635–649 (1998).

3. Boyartchuck, V.L., Ashby, M.N. & Rine, J. Modulation of ras and a-factor function by carboxyl-terminal proteolysis. Science 275, 1796–1800 (1997).

4. Sullivan, T. et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J. Cell. Biol. 147, 913–920 (1999).

5. Fisher, D.Z., Chaudhary, N. & Blobel, G. cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins. Proc. Natl Acad. Sci. USA 83, 6450–6454 (1986).

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