Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia-Reference-Cited by-同舟云学术

Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia

Published:2019-12-06 Issue:12 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Kaneshwaran Kirusanthy¹^ORCID,Olah Marta²,Tasaki Shinya³⁴,Yu Lei³⁴,Bradshaw Elizabeth M.²^ORCID,Schneider Julie A.³⁴^ORCID,Buchman Aron S.³⁴^ORCID,Bennett David A.³⁴^ORCID,De Jager Philip L.²^ORCID,Lim Andrew S. P.¹^ORCID

Affiliation:

1. Division of Neurology, Department of Medicine, Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Toronto, Canada.

2. Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.

3. Rush Alzheimer Disease Center, Rush University Medical Center, Chicago, IL, USA.

4. Department of Neurological Sciences; Rush University, Chicago, IL, USA.

Abstract

Poor sleep in older adults is associated with aging of the brain’s resident innate immune cells and impaired cognition.

Funder

National Institutes of Health

Canadian Institutes of Health Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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