Regulation of energy rheostasis by the melanocortin-3 receptor-Reference-Cited by-同舟云学术

Regulation of energy rheostasis by the melanocortin-3 receptor

Published:2018-08-03 Issue:8 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Ghamari-Langroudi Masoud¹^ORCID,Cakir Isin¹²^ORCID,Lippert Rachel N.¹³^ORCID,Sweeney Patrick²,Litt Michael J.¹,Ellacott Kate L. J.¹⁴^ORCID,Cone Roger D.¹²^ORCID

Affiliation:

1. Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 702 Light Hall, Nashville, TN 37232, USA.

2. Life Sciences Institute and Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109–2216, USA.

3. Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany.

4. University of Exeter Medical School, Exeter, UK.

Abstract

The melanocortin-3 receptor acts as a rheostat on energy homeostasis through presynaptic inhibition of MC4R neuronal activity.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference38 articles.

1. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome;Fan W.;Nature,1997