Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass-Reference-Cited by-同舟云学术

Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

Published:2000-09 Issue:1 Volume:26 Page:97-102
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Chen Airu S.,Marsh Donald J.,Trumbauer Myrna E.,Frazier Easter G.,Guan Xiao-Ming,Yu Hong,Rosenblum Charles I.,Vongs Aurawan,Feng Yue,Cao Linhai,Metzger Joseph M.,Strack Alison M.,Camacho Ramon E.,Mellin Theodore N.,Nunes Christian N.,Min William,Fisher Jill,Gopal-Truter Shobhna,MacIntyre D. Euan,Chen Howard Y.,Van der Ploeg Lex H.T.

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng0900_97.pdf

Reference30 articles.

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2. Chagnon, Y.C. et al. Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the quebec family study. Mol. Med. 3, 663–673 ( 1997).

3. Yeo, G.S.H. et al. A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nature Genet. 20, 111–112 (1998).

4. Vaisse, C., Clement, K., Guy-Grand, B. & Froguel, P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nature Genet. 20, 113– 114 (1998).

5. Michaud, E.J. et al. A molecular model for the genetic and phenotypic characteristics of the mouse lethal yellow (Ay) mutation. Proc. Natl Acad. Sci. USA 91, 2562–2566 (1994).

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