Pharmacological activation of STING blocks SARS-CoV-2 infection-Reference-Cited by-同舟云学术

Pharmacological activation of STING blocks SARS-CoV-2 infection

Published:2021-05-28 Issue:59 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Li Minghua¹^ORCID,Ferretti Max²^ORCID,Ying Baoling³,Descamps Hélène⁴^ORCID,Lee Emily⁵^ORCID,Dittmar Mark¹^ORCID,Lee Jae Seung¹^ORCID,Whig Kanupriya²⁶^ORCID,Kamalia Brinda²⁶^ORCID,Dohnalová Lenka⁴^ORCID,Uhr Giulia⁴,Zarkoob Hoda⁵,Chen Yu-Chi⁵,Ramage Holly⁷^ORCID,Ferrer Marc⁵,Lynch Kristen²,Schultz David C.²⁶^ORCID,Thaiss Christoph A.⁴,Diamond Michael S.³⁸⁹^ORCID,Cherry Sara¹²⁴

Affiliation:

1. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

2. Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA.

3. Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

4. Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

5. National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.

6. High Throughput Screening Core, University of Pennsylvania, Philadelphia, PA 19104, USA.

7. Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

8. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

9. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Abstract

Pharmacological activation of STING blocks SARS-CoV-2 infection including variants of concern in vitro and in vivo.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference55 articles.

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