Foundations of human reasoning in the prefrontal cortex

Abstract

Selecting the most successful strategy The brain's prefrontal cortex helps us to make decisions in an uncertain and constantly changing environment. Donoso et al. present a model of human reasoning as an algorithm implemented in the prefrontal cortex (see the Perspective by Hare). Brain-imaging experiments supported this model. Depending on the prevailing circumstances, human reasoning can either adapt ongoing behavioral strategies or switch to previously learned strategies. Only when neither approach is appropriate will the brain create new strategies. Science , this issue p. 1481 , see also p. 1446