SIR1, an Upstream Component in Auxin Signaling Identified by Chemical Genetics-Reference-Cited by-同舟云学术

SIR1, an Upstream Component in Auxin Signaling Identified by Chemical Genetics

Published:2003-08-22 Issue:5636 Volume:301 Page:1107-1110
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Zhao Yunde¹²³,Dai Xinhua¹²³,Blackwell Helen E.¹²³,Schreiber Stuart L.¹²³,Chory Joanne¹²³

Affiliation:

1. Section of Cell and Developmental Biology, Division of Biological Sciences, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093–0116, USA.

2. Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute (HHMI), Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.

3. The Plant Biology Laboratory, HHMI and The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Abstract

Auxin is a plant hormone that regulates many aspects of plant growth and development. We used a chemical genetics approach to identify SIR1 , a regulator of many auxin-inducible genes. The sir1 mutant was resistant to sirtinol, a small molecule that activates many auxin-inducible genes and promotes auxin-related developmental phenotypes. SIR1 is predicted to encode a protein composed of a ubiquitin-activating enzyme E1–like domain and a Rhodanese-like domain homologous to that of prolyl isomerase. We suggest a molecular context for how the auxin signal is propagated to exert its biological effects.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference29 articles.

1. Auxin regulates SCFTIR1-dependent degradation of AUX/IAA proteins

2. Genetic approaches to auxin action

3. G. Hagen, T. J. Guilfoyle, Mol. Cell. Biol.5, 1197 (1985).

4. Rapid induction of specific mRNAs by auxin in pea epicotyl tissue

5. Plant Development: Regulation by Protein Degradation

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