Design, Synthesis, and Biological Evaluation of Β-Carboline-Cinnamic Acid Derivatives as Dyrk1a Inhibitors in the Treatment of Diabetes

Author:

Guan Li,Li Aiyun,Song Pengfei,Su Wanzhen,Zhang Shengjie,Jiao Xiangying,Li Weize

Publisher

Elsevier BV

Reference36 articles.

1. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action;L A Thielen;Cell Metab,2020

2. Disrupting the DREAM complex enables proliferation of adult human pancreatic ? cells;P Wang;J. Clin. Invest

3. DYRK1A inhibitors as potential therapeutics for ?-cell regeneration for diabetes;K Kumar;J. Med. Chem,2021

4. TXNIP inhibition in the treatment of type 2 diabetes mellitus: design, synthesis, and biological evaluation of quinazoline derivatives;A Y Li;J. Enzyme Inhib. Med. Chem,2023

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