Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action-Reference-Cited by-同舟云学术

Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action

Published:2020-09 Issue:3 Volume:32 Page:353-365.e8
ISSN:1550-4131
Container-title:Cell Metabolism
language:en
Short-container-title:Cell Metabolism

Author:

Thielen Lance A.,Chen Junqin,Jing Gu,Moukha-Chafiq Omar,Xu Guanlan,Jo SeongHo,Grayson Truman B.,Lu Brian,Li Peng,Augelli-Szafran Corinne E.,Suto Mark J.,Kanke Matt,Sethupathy Praveen,Kim Jason K.,Shalev Anath

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference37 articles.

1. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines;Asfari;Endocrinology,1992

2. Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells;Cha-Molstad;J. Biol. Chem.,2009

3. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes;Chen;FASEB J.,2008

4. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis;Chen;Diabetes,2008

5. TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling;Chen;Am. J. Physiol. Heart Circ. Physiol.,2016

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